Talk:Saviors of the Tower/26/@comment-28089742-20160406042440/@comment-3083005-20160406072239

You can have 4 effects active, when you active the 5th then the first one will be removed.

The problem here however is that Circe's active skill also "Invalidate all Damage-reducing Skills", meaning that damage reduction skills like that of Ootengu don't work.